50/F WITH BACKACHE SINCE 20 DAYS AND INABILITY TO USE ALL FOUR LIMBS SINCE 10 DAYS.

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Unit 6 admission:

Interns 

K. Nikhil reddy

K.Divya

M. Swarna 

 B.Manivarma

Juveria 


 Dr. Manasa(pgy1)

Dr. Rashmitha (pgy2) 

Dr.  Sai Radha(pgy3)

Dr. Arjun kumar (asst.prof.)

Dr.Rakesh Biswas (HOD)

 A 50 year old female , labourer by occupation, came to casuality with Chief complaints of backache since 20 days, inability to use all four limbs  since 10 days.

Patient was apparently asymptomatic 2 months back, later she developed backache, sudden in onset, gradually progressive for which she went to local hospital and relieved with medication.Now again ,she complaints of backache since 20 days,  took some medication and didn't get relieved.

 H/o proximal Lowerlimb weakness since 10 days,sudden in onset, gradually progresed in order--proximal lower limbs  -distal lower limbs-proximal upper limbs -distal lower limbs.D

Difficultyin combing of hair ,taking food to mouth.

Difficulty in buttoning and unbuttoning, mixing of food.

Difficulty in squatting, getting up from squatting position,climbing stairs up and down .

Difficulty in wearing of chappals+,tripping of toes+.

Difficulty in lifting the head off the pillows +.

Difficulty in rolling over bed, getting up from bed+.

No difficulty in breathing.

No diurnal variation of weakness, but gets relief after tramadol injection for 2 hours.

 Past history:

Not a k/c/o DM,HTN, TB, asthma, epilepsy, CAD, CVA.

H/o Total abdominal hysterectomy with bilateral salpingo-oophorectomy due to DUB UNDER SA in 2009.


General examination:

Nno pallor, icterus, cyanosis, clubbing, lymphadenopathy, pedal edema.

Vitals:

Temperature:99F

BP:110/80mmHg.

PR:78 bpm

RR:30 cpm

Spo2:98%at room air

GRBS:100 mg/dl.


Systemic examination:

CNS:

Patient is conscious, oriented to time,place , person, cooperative.

HMF- normal

Cranialnerves : intact

Motor examination:


                                 Rt.                 Lt.

1.Tone

Upper limbs.       Normal         Normal

Lower limbs.       Normal.         Normal

2.power

Upper limbs.         4-/5.                  4-/5

Lowerlimbs.         4-/5.                   4-/5

Hand grip.            100%.                  100%

3. Reflexes 

                                          Rt.                Lt.

 1.Corneal                         Present.      Present

 2. Conjunctival                 Present.      Present

 3. Pharyngeal                  Present.      Present

 4 Palatal.                         Present.      Present 

  5.plantar                           Flexor       flexor 

  6.  Biceps                           2+                2+                  7. triceps                              2+                2+

  8.supinator.                         2+                2+

  9. Knee.                               2+                2+

10. Ankle                             2+                2+

11 . plantar.                    Flexor.            Flexor.           

 Cerebellar examination : Normal

Sensory examination:Normal

Autonomic nervous system-Normal

 Spine examination: No tenderness.

Meningeal signs:

Neck rigidity,Kernigs and brudzinski signs -. Negative.

CVS: S1, S2HEARD, no murmurs.

RS: BAE+,NVBS HEARD.

P/A: SOFT, NON TENDER, BOWEL SOUNDS+.




Investigations:

CBP:
CUE:

ABG

LFT

RFT

THYROID PROFILE

SEROLOGY

RBS

CHEST X RAY

X RAY- SIJ

ECG

USG- ABDOMEN

USG -NECK

MRI BRAIN

MRI CSPINE WITH WHOLE SPINE SCREENING

PROVISIONAL DIAGNOSIS:
QUADRIPARESIS UNDER EVALUATION SECONDARY TO ? MYOPATHY ?BONY(VERTEBRAL) LYTIC LESION?MULTIPLE MYELOMA.

TREATMENT GIVEN:
1 . INJ. OPTINEURON 1 AMP IN 100 ML NS IV/OD
2.TAB. MYORIL 8 MG PO/BD
3.INJ. PAN 40 MG IV OD
4.TAB. NEUROBION FORTE PO/OD
5. INJ. TRAMADOL 1 AMP IN 100 ML NS IV/BD.


On 14/3/2021
S: backache decreased, no fresh complaints.
O: Temp:98.6F
   BP:110/80 mmhg
   PR:74bpm
   RR:26 cpm
   Spo2: 98%at room air.
   CNS:Patient is conscious, oriented to time,place , person, cooperative.

HMF- normal

Cranialnerves : intact

Motor examination:  

                              Rt.                 Lt.

1.Tone

Upper limbs.       Normal         Normal

Lower limbs.       Normal.         Normal

2.power

Upper limbs.         4-/5.                  4-/5

Lowerlimbs.         4-/5.                   4-/5

Hand grip.            100%.                  100%

3. Reflexes 

                                          Rt.                Lt.

 1.Corneal                         Present.      Present

 2. Conjunctival                 Present.      Present

 3. Pharyngeal                  Present.      Present

 4 Palatal.                         Present.      Present 

  5.plantar                           Flexor       flexor 

  6.  Biceps                           2+                2+                  7. triceps                              2+                2+

  8.supinator.                         2+                2+

  9. Knee.                               2+                2+

10. Ankle                             2+                2+

11 . plantar.                    Flexor.            Flexor.           

 Cerebellar examination : Normal

Sensory examination:Normal

Autonomic nervous system-Normal

 Spine examination: No tenderness.

Meningeal signs:

Neck rigidity,Kernigs and brudzinski signs -. Negative 

  RS:BAE+, NVBS HEARD  

  CVS: S1, S2 heard, no murmurs. 

   P/A:soft, non tender, no organomegaly.

A:QUADRIPARESIS UNDER EVALUATION SECONDARY TO ? MYOPATHY ?BONY(VERTEBRAL) LYTIC LESION?MULTIPLE MYELOMA.
P:
1. INJ. OPTINEURON 1 AMP IN 100 ML NS IV/OD
2.TAB. MYORIL 8 MG PO/TID
3.TAB. NEUROBION FORTE PO/OD
4. INJ. TRAMADOL 1 AMP IN 100 ML NS IV/BD.
5.INJ. PAN 40 MG IV OD
6. INJ. ZOFER 4 MG IV /TID
7.SINGLE BREATH COUNT MONITORING
8. PHYSIOTHERAPY OF BOTH LOWER LIMBS.



On 15/3/2021
S: backache decreased, no fresh complaints.
O:  BP:110/80 mmhg
   PR:68bpm
   RR:20 cpm
   Spo2: 98%at room air.
   CNS:Patient is conscious, oriented to time,place , person, cooperative.

HMF- normal

Cranialnerves : intact

Motor examination:

                                 Rt.                 Lt.

1.Tone

Upper limbs.       Normal         Normal

Lower limbs.       Normal.         Normal

2.power

Upper limbs.         4-/5.                  4-/5

Lowerlimbs.         4-/5.                   4-/5

Hand grip.            100%.                  100%

3. Reflexes 

                                          Rt.                Lt.

 1.Corneal                         Present.      Present

 2. Conjunctival                 Present.      Present

 3. Pharyngeal                  Present.      Present

 4 Palatal.                         Present.      Present 

  5.plantar                           Flexor       flexor 

  6.  Biceps                           2+                2+                  7. triceps                              2+                2+

  8.supinator.                         2+                2+

  9. Knee.                               2+                2+

10. Ankle                             2+                2+

11 . plantar.                    Flexor.            Flexor.           

 Cerebellar examination : Normal

Sensory examination:Normal

Autonomic nervous system-Normal

 Spine examination: No tenderness.

Meningeal signs:

Neck rigidity,Kernigs and brudzinski signs -. Negative 

  RS:BAE+, NVBS HEARD  

  CVS: S1, S2 heard, no murmurs. 

   P/A:soft, non tender, no organomegaly.

A:QUADRIPARESIS UNDER EVALUATION SECONDARY TO ? MYOPATHY ?BONY(VERTEBRAL) LYTIC LESION?MULTIPLE MYELOMA.
P:
1. INJ. METHYL PREDNISOLONE 1 GM IN 100 ML NS OVER 20 MINUTES.
2.TAB. MYORIL 8 MG PO/TID
3.TAB. NEUROBION FORTE PO/OD
4. INJ. TRAMADOL 1 AMP IN 100 ML NS IV/BD.
5.INJ. PAN 40 MG IV OD
6. INJ. ZOFER 4 MG IV /TID
7.SINGLE BREATH COUNT MONITORING
8. PHYSIOTHERAPY OF BOTH LOWER LIMBS.


On 16/3/2021

S: backache decreased, no fresh complaints.
O:  BP:100/70 mmhg
   PR:74bpm
   RR:20 cpm
   Spo2: 98%at room air.
   CNS:Patient is conscious, oriented to time,place , person, cooperative.

HMF- normal

Cranialnerves : intact

Motor examination:

                                 Rt.                 Lt.

1.Tone

Upper limbs.       Normal         Normal

Lower limbs.       Normal.         Normal

2.power

Upper limbs.         4-/5.                  4-/5

Lowerlimbs.         4-/5.                   4-/5

Hand grip.            100%.                  100%

3. Reflexes 

                                          Rt.                Lt.

 1.Corneal                         Present.      Present

 2. Conjunctival                 Present.      Present

 3. Pharyngeal                  Present.      Present

 4 Palatal.                         Present.      Present 

  5.plantar                           Flexor       flexor 

  6.  Biceps                           2+                2+                  7. triceps                              2+                2+

  8.supinator.                         2+                2+

  9. Knee.                               2+                2+

10. Ankle                             2+                2+

11 . plantar.                    Flexor.            Flexor.           

 Cerebellar examination : Normal

Sensory examination:Normal

Autonomic nervous system-Normal

 Spine examination: No tenderness.

Meningeal signs:

Neck rigidity,Kernigs and brudzinski signs -. Negative 

  RS:BAE+, NVBS HEARD  

  CVS: S1, S2 heard, no murmurs. 

   P/A:soft, non tender, no organomegaly.

A:QUADRIPARESIS UNDER EVALUATION SECONDARY TO ? MYOPATHY ?BONY(VERTEBRAL) LYTIC LESION?MULTIPLE MYELOMA.
P:
1. INJ. OPTINEURON 1 AMP IN 100 ML NS IV/OD.
2. INJ. TRAMADOL 1 AMP IN 100 ML NS IV/BD.
3.TAB. PAN 40 MG PO/OD
4.TAB. ULTRACET 1/2 TAB. PO/QID.
5. PHYSIOTHERAPY OF BOTH LOWER LIMBS
6. SYP. CREMAFFIN PLUS 10 ML PO/TID 


On 17/3/2021
S: backache decreased, no fresh complaints.
O:  BP:110/70 mmhg
   PR:76bpm
   RR:20 cpm
   Spo2: 98%at room air.
   CNS:Patient is conscious, oriented to time,place , person, cooperative.

HMF- normal

Cranialnerves : intact

Motor examination:

                                 Rt.                 Lt.

1.Tone

Upper limbs.       Normal         Normal

Lower limbs.       Normal.         Normal

2.power

Upper limbs.         4-/5.                  4-/5

Lowerlimbs.         4-/5.                   4-/5

Hand grip.            100%.                  100%

3. Reflexes 

                                          Rt.                Lt.

 1.Corneal                         Present.      Present

 2. Conjunctival                 Present.      Present

 3. Pharyngeal                  Present.      Present

 4 Palatal.                         Present.      Present 

  5.plantar                           Flexor       flexor 

  6.  Biceps                           2+                2+                  7. triceps                              2+                2+

  8.supinator.                         2+                2+

  9. Knee.                               2+                2+

10. Ankle                             2+                2+

11 . plantar.                    Flexor.            Flexor.           

 Cerebellar examination : Normal

Sensory examination:Normal

Autonomic nervous system-Normal

 Spine examination: No tenderness.

Meningeal signs:

Neck rigidity,Kernigs and brudzinski signs -. Negative 

  RS:BAE+, NVBS HEARD  

  CVS: S1, S2 heard, no murmurs. 

   P/A:soft, non tender, no organomegaly.

A:QUADRIPARESIS UNDER EVALUATION SECONDARY TO ? MYOPATHY ?BONY(VERTEBRAL) LYTIC LESION?MULTIPLE MYELOMA.
P:
1. INJ. OPTINEURON 1 AMP IN 100 ML NS IV/OD.
2. INJ. TRAMADOL 1 AMP IN 100 ML NS IV/BD.
3.TAB. PAN 40 MG PO/OD
4.TAB. ULTRACET 1/2 TAB. PO/QID.
5. PHYSIOTHERAPY OF BOTH LOWER LIMBS
6. SYP. CREMAFFIN PLUS 10 ML PO/TID 


Patient discharged on 17/3/2021.

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